Your hands now start to have some relevance and context and you will be guided by Omaha Poker flop strategy as what to do next. You can see what your hand is and what it could improve to. Remember you can use only two of your four cards. Failure to do is is one of the most common errors in online poker and online poker strategy that there is.
You also have to be wary of what the best possible hand could be. Omaha Poker flop strategy says that if there is a pair of the table they could mean a full house and possibly even quads. Pay close attention to the betting to see if there are any tells that your opponents may be holding one of these hands.
Bluffing should be done less in Omaha for two reasons. First of all, with everyone getting four cards there is a greater chance that someone has the key card in question, especially in a long-handed game. Second of all, Omaha tends to be a far looser game and so you will find that most of your bluffs are called. Be mindful of both of these things when putting your Omaha Poker flop strategy into effect.
Even if you are not bluffing you may find that you don’t have the best hand. It is very common in Omaha for one full house to beat another or quads beating a full house which beats an Ace-high flush.
Given this it sometimes helps to be more conservative than you otherwise would be when you don’t have the nuts.
If you don't have a pair or straight or flush opportunities then fold. Someone is definitely going to have something and that doesn't look like being you.
Bluffing tends to be a waste of time here due to the looseness of the game.